Data from: Positive selection in coding regions and motif duplication in regulatory regions of bottlenose dolphin MHC class II genes

Heidi J.T. Pagán, Tatiana Ferrer, Gregory O'Corry-Crowe, Heidi J. T. Pagán & Greg O’Corry-Crowe
The vertebrate immune response is mediated through highly adaptive, quickly evolving cell surface receptors, the major histocompatibility complex (MHC). MHC molecules bind and present a diverse array of pathogenic molecules and trigger a cascade of defenses. Use of MHC variation as a marker for population health has also evolved quickly following advances in sequencing methods. We applied a combination of traditional and next generation sequencing methodology to characterize coding (peptide binding region) and regulatory (proximal...
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