Data from: Brain myo-inositol as a potential marker of amyloid-related pathology: a longitudinal study.

Olga Voevodskaya, Konstantinos Poulakis, Pia Sundgren, Danielle Van Westen, Sebastian Palmqvist, Lars Olof Wahlund, Erik Stomrud, Oskar Hansson & Eric Westman
Objective: To investigate the association between longitudinal changes in proton magnetic spectroscopy (MRS) metabolites and amyloid pathology in non-demented individuals; to explore the relationship between MRS and cognitive decline. Methods: In this longitudinal multiple time point study (a subset of the Swedish BioFINDER) we included cognitively healthy participants, individuals with subjective cognitive decline and mild cognitive impairment (MCI). MRS was acquired serially in 294 participants (670 individual spectra) from the posterior cingulate/precuneus. Using mixed-effects models,...
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