Data from: Pleiotropy can be effectively estimated without counting phenotypes through the rank of genotype-phenotype map

Xun Gu
Though pleiotropy, the capability of a gene affecting multiple phenotypes, has been well-known as one of common gene properties, a quantitative estimation remains a great challenge, simply because of the phenotype complexity. Not surprisingly, it is hard for general readers to understand how, without counting phenotypes, gene pleiotropy can be effectively estimated from the genetics data. In this article we extensively discussed the Gu-2007-method (Genetics 175: 1813-1822) that estimated pleiotropy from the protein sequence analysis....
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