Data from: The effect of a transient immune activation on subjective health perception in two placebo controlled randomised experiments

Mats Lekander, John Axelsson, Caroline Olgart Höglund, Anna Andreasson, Martin Ingvar, Lisa Lidberg, Torbjörn Åkerstedt & Bianka Karshikoff
Background Patient-reported outcomes predict mortality and play increasingly important roles in care, but factors that modify central measures such as health ratings have been little investigated. Building on designated immune-to-brain pathways, we aimed to determine how a short-term induced inflammation response impacts self-reported health status. Methods Lipopolysaccharide injections were used to provoke acute systemic inflammatory responses in healthy men and women and were compared to placebo in two double-blind randomized experiments. In Experiment 1, 8...
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