Data from: Persistent firing in LEC III neurons is differentially modulated by learning and aging

Carmen Lin, Venus Sherathiya, M Matthew Oh & John Disterhoft
Whether and how persistent firing in lateral entorhinal cortex layer III (LEC III) supports temporal associative learning is still unknown. In this study, persistent firing was evoked in vitro from LEC III neurons from young and aged rats that were behaviorally naïve or trained on trace eyeblink conditioning. Persistent firing ability from neurons from behaviorally naïve aged rats was lower compared to neurons from young rats. Neurons from learning impaired aged animals also exhibited reduced...
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