High MHC diversity confers no advantage for phenotypic quality and reproductive performance in a wild birdEwa Pikus, Peter Dunn & Piotr Minias
Genes of the major histocompatibility complex (MHC) encode antigen binding molecules and are an integral part of the acquired immune response of vertebrates. In general, high individual MHC diversity is expected to increase fitness by broadening the spectrum of pathogens recognized by the immune system, in accordance with the heterozygote advantage mechanism. On the other hand, the optimality hypothesis assumes that individuals with optimal (intermediate), rather than maximum diversity of the MHC will achieve the...
1 citation reported since publication in 2022.
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