Data from: Resource limitation prevents the emergence of drug resistance by intensifying within-host competition

Nina Wale, Derek G. Sim, Matthew J. Jones, Rahel Salathe, Troy Day & Andrew F. Read
Slowing the evolution of antimicrobial resistance is essential if we are to continue to successfully treat infectious diseases. Whether a drug-resistant mutant grows to high densities, and so sickens the patient and spreads to new hosts, is determined by the competitive interactions it has with drug-susceptible pathogens within the host. Competitive interactions thus represent a good target for resistance management strategies. Using an in vivo model of malaria infection, we show that limiting a resource...
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