Data from: Widespread genetic incompatibilities between first-step mutations during parallel adaptation of Saccharomyces cerevisiae to a common environment

Jasmine Ono, Aleeza C. Gerstein & Sarah P. Otto
Independently evolving populations may adapt to similar selection pressures via different genetic changes. The interactions between such changes, such as in a hybrid individual, can inform us about what course adaptation may follow and allow us to determine whether gene flow would be facilitated or hampered following secondary contact. We used Saccharomyces cerevisiae to measure the genetic interactions between first-step mutations that independently evolved in the same biosynthetic pathway following exposure to the fungicide nystatin....
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