An evaluation of inbreeding measures using a whole genome sequenced cattle pedigree

Tom Druet, Setegn Worku Alemu, Naveen Kumar Kadri, Pierre Faux, Chad Harland, Carole Charlier & Armando Caballero
The estimation of the inbreeding coefficient (F) is essential for the study of inbreeding depression (ID) or for the management of populations under conservation. Several methods have been proposed to estimate the realized F using genetic markers, but it remains unclear which one should be used. Here we used whole-genome sequence data for 245 individuals from a Holstein cattle pedigree to empirically evaluate which estimators best capture homozygosity at variants causing ID, such as rare...
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These counts follow the COUNTER Code of Practice, meaning that Internet robots and repeats within a certain time frame are excluded.
What does this mean?