Data from: Human endometrial transcriptome and progesterone receptor cistrome reveal important pathways and epithelial regulators

Ru-Pin Alicia Chi, Tianyuan Wang, Nyssa Adams, San-Pin Wu, Steven Young, Thomas Spencer & Francesco DeMayo
Context. Poor uterine receptivity is one major factor leading to pregnancy loss and infertility. Understanding the molecular events governing successful implantation is hence critical in combating infertility. Objective. To define PGR-regulated molecular mechanisms and epithelial roles in receptivity. Design. RNA-seq and PGR-ChIP-seq were conducted in parallel to identify PGR-regulated pathways during the WOI in endometrium of fertile women. Setting. Endometrial biopsies from the proliferative and mid-secretory phases were analyzed. Patients or Other Participants. Participants were...
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