Cellular dataset for: The anterior Hox gene ceh-13 and elt-1/GATA activate the posterior Hox genes nob-1 and php-3 to specify posterior lineages in the C. elegans embryo

Amanda Zacharias, John Isaac Murray, Elicia Preston, Jeremy Crawford, Jonathan Rumley, Prativa Amom, Breana Anderson, Priya Sivaramakrishnan, Shaili Patel, Barrington Bennett, Teddy Lavon & Felicia Peng
Hox transcription factors play a conserved role in specifying positional identity during animal development, with posterior Hox genes typically repressing the expression of more anterior Hox genes. Here, we dissect the regulation of the posterior Hox genes nob-1 and php-3 in the nematode C. elegans. We show that nob-1 and php-3 are co-expressed in gastrulation-stage embryos in cells that previously expressed the anterior Hox gene ceh-13. This expression is controlled by several partially redundant transcriptional...
1 citation reported since publication in 2021.
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