Tissue-specific circadian transcriptional regulation

Jake Yeung
Circadian rhythms in physiology and behavior evolved to resonate with daily cycles in the external environment. In mammals, organs orchestrate temporal physiology over the 24-hour day, which requires extensive gene expression rhythms targeted to the right tissue. Although a core set of gene products oscillate across virtually all cell-types, gene expression profiling across tissues over the 24-hour day showed that rhythmic gene expression programs are tissue-specific. We highlight recent progress in uncovering how the circadian...
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