3.2.1 Designing an interface and cell for cellular biosensing

Cells are very intelligent and smart transducers because they transmit various molecular signals in response to extracellular stimuli, both chemically and physically. This fact suggests that living cells can act as sensors in qualified analysis. Such cellular biosensors for qualified analyses can be employed as smart tool in high-throughput analysis in clinical drug discovery. Clinical drug discovery in most cases begins with molecular screening in order to select a lead substance. This process is a...