3.2.3 Living cell-based gas sensor system for the detection of acetone in air

Ulrich Bohrn, Evamaria Stütz, Maximilian Fleischer, Michael J. Schöning & Patrick Wagner
In this study, a cell-based gas biosensor is presented, which can be used for the detection of gaseous organic compounds in ambient air. The response of living human nasal cells (RPMI 2650) towards the direct exposure of gaseous substances is monitored with a multi-parametric sensor system using an exposure time of 10-15 minutes. Changes in the cellular impedance, oxygen consumption rate and acidification rate are recorded immediately after the exposure and represent the metabolic cell...