P1.1.6 Flow chamber for living cell detection by SPR

Fuyin Dou, Xinglong Yu, Lili Ding & Fangfang Liu
The detection of molecular interactions on living cells using SPR is attracting more and more attention. This paper presents a flow chamber design for maintaining suitable physiological conditions of living cells during detection. It includes a microfluidic flow system providing precise injection of culture media or reagent and a themoregulator assuring suitable temperature. Experimental results demonstrate that the flow chamber is reliable for detecting living cells.