P1.2.11 An Integrated Electrophoresis Microchip for Label-free Detection Using Surface Plasmon Resonance Image

X. Chen, H. Y. Cai, L. L. Zhang, H. Li, J. H. Sun, D. F. Cui & Y. P. Chao
In this work, a novel microfluidic-based electrophoresis method combined with surface plasmon resonance image (SPRI) has been developed for electrokinetic fluid transport and label-free detection. The integrated microfluidic chip was designed and fabricated by MEMS technology. A PDMS layer with double T-type microchannels for electrophoresis was fabricated and then directly bonded on a specialized SPR sensing substrate. In order to avoid the electrochemical corrosion of the metallic SPR surface, a microarray of rectangle gold spots...