P2.1.5 A new Approach to Tricyclic Antidepressants Detection Based on Graphite Microsensors Fabricated by an Innovative Method

Beata Rozum, Marek Dawgul, Jerzy Kruk, Wladyslaw Torbicz & Dorota G. Pijanowska
In this study a novel low-cost method of amperometric sensors’ fabrication based on thick-film technique on solid support and their analytical application are presented. Complete graphite/silver cell sensors were fabricated with the new technology using a desk-top XYZ-dispensing robot and printing pastes. The amperometric sensors were applied for the detection of three selected tricyclic antidepressant drugs (TCAs): imipramine (IMI), amitriptyline (AMI) and doxepin (DOX). The monitoring of TAC concentration in patients’ body fluids is need,...