P2.5.2 Electrical Monitoring of Layer-by-Layer Adsorption of Oppositely Charged Macromolecules by Means of Capacitive Field-Effect Devices

M. Weil, A. Poghossian, M. J. Schöning & A. G. Cherstvy
Field-effect-based semiconductor devices for the label-free detection of molecular interactions represent a promising platform for biosensor applications. However, a quantitative physical understanding of experimental observations is still not complete in many situations. Therefore, it is important to elucidate the possibilities and limitations of field-effect sensors for the detection of charged macromolecules. In this work, a capacitive electrolyteinsulator-semiconductor field-effect sensor has been applied for real-time in-situ electrical monitoring of a layer-bylayer build-up of polyelectrolyte multilayers. The...