C8.3 - Cell-Based in Vitro Systems for Continous Monitoring of Bioenergetics and Cell Impedance

R. Ehret, S. Drechsler, A. Kob, M. Wego & St. Ortinau
The identification of pharmacodynamic properties of drug substances and the prediction of toxicity in early phases of drug development are major challenges of advanced in vitro methods. Therefore the evaluation of short-term effects of receptor signaling studies and the investigation of long-term effects mediated by toxins and xenobiotics are essential. The Bionas Discovery label-free assay family measures physiological functions of cell lines and primary cells using non-invasive assays in a physiological controlled environment which provides...