C5.2 - Miniaturized drug delivery system TUDOS with accurate metering of microliter volumes

M. Richter, M. Wackerle, S. Kibler, M. Biehl, T. Koch, C. Müller, R. Halter, J. Nuffer & O. Zeiter
A miniaturized drug delivery system for accurate dosing of drugs for therapy of cancer is presented. The weight of the system is less than 8 grams. Silicon micropumps with a stroke volume of 88 nl, and blocking pressure of 6 bar, drive the system. A novel and accurate flow monitoring principle based on capacitance measurement was developed and implemented into the drug delivery system. To prevent free flow, a self blocking safety valve was adapted...