BS6.4 - A fluorescent biosensor based on molybdenum disulfide (MoS2) nanosheets and protein aptamer for sensitive detection of carcinoembryonic antigen

L. Zhao, M. Cheng, G. Liu, H. Lu, Y. Gao & G. Lu
Simple, rapid, sensitive detection of tumor biomarker carcinoembryonic antigen (CEA) is of great importance for the screening, diagnosis and prognosis evaluation of various gastroenteric tumor. This paper presents a "turn-on" flourescent biosensor based on molybdenum disulfide(MoS2) nanosheets and fluorophore labeled protein aptamer for rapid and sensitive detection of CEA protein. CEA aptamer probe can be adsorbed on the surface of MoS2 nanosheets in close proximity via van der Waals force, triggering fluorescence resonance energy transfer,...
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