Improving Contig Binning Of Metagenomic Data Using D2S Oligonucleotide Frequency Dissimilarity

Wang Ying, Wang Kun, & Sun Fengzhu
d2SBin is easy-to-use contig-binning improving tool, which adjusted the contigs among bins based on the output of any existing binning tools. The tool is taxonomy-free only on the k-tuples for single metagenomic sample. d2SBin is based on the mechanism that relative sequence compositions are similar across different regions of the same genome, but differ between genomes. Current tools generally used the normalized frequency of k-tuple directly, which actually is the absolute instead of relative sequence...
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