PERFECTA – A Superfluorinated Molecular Probe for MRI

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Magnetic resonance imaging (MRI) has had a transformative effect in modern medicine. A hot-spot imaging technique utilises another nucleus (such as 19F) to provide a second coloured layer, information which is independent to the anatomical details provided by the grey-scale proton NMR image. PERFECTA is a contrast agent which contains 36 equivalent 19F atoms and shows a single intense resonance peak. It is very stable and is easily synthesised using a one-step reaction. The hydrocarbon...
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