FoldX as Protein Engineering Tool: Better Than Random Based Approaches?

Oliver Buß, Jens Rudat & Katrin Ochsenreither
Improving protein stability is an important goal for basic research as well as for clinical and industrial applications but no commonly accepted and widely used strategy for efficient engineering is known. Beside random approaches like error prone PCR or physical techniques to stabilize proteins, e.g. by immobilization, in silico approaches are gaining more attention to apply target-oriented mutagenesis. In this review different algorithms for the prediction of beneficial mutation sites to enhance protein stability are...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.