Xenorhabdus nematophila RelE antitoxin

Bacterial chromosomal ‘toxin-antitoxin systems’ (TA systems) are involved in various cell functions such as stress response, promoting cell cycle arrest and bringing about the onset of programmed cell death. Unlike RelBE TA module of Escherichia coli, genome of Xenorhabdus nematophila has two separate TA modules for RelB and RelE. Here RelE being the toxin bears its own antitoxin and RelB antitoxin bears its separate toxin counterpart. More interestingly these modules are located distantly in genome....
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