Formyl peptide receptor 1 (FPR1)

Formyl peptide receptor 1 (FPR1) is a cell surface receptor protein, belonging to G protein-coupled receptor (GPCR) super-family, that binds and is activated by oligopeptides containing the N-Formylmethionine which are released by microorganisms and injured tissues. Hence, FPR1 is an important component of the immune system operating on host defense and inflammation. It is known that its high expression in several cancers although its function in tumor invasion and metastasis is poorly known. In this...
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