Selenophosphate Synthetase 2 (SEPHS2)

Selenophosphate synthetase 2 (SEPHS2) synthesizes from selenide and ATP the selenophosphate that represents the selenium donor used to synthesize selenocysteine (Sec), which is co-translationally incorporated into the selenoproteins. Only few information are reported in literature about SEPHS2 involvement in cancer. Thus, it should be interesting to understand what is its functional role in cancer development and progression. In this work, since up to now no structure was experimentally determined for SEPHS2, we decided to analyze...
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