DNA methylome of human peripheral blood mononuclear cells from the YH Han Chinese individual

Y Li, J Zhu, G Tian, N Li, Q Li, M Ye, H Zheng, J Yu, H Wu, J Sun, H Zhang, Q Chen, R Luo, M Chen, Y He, X Jin, Q Zhang, C Yu, G Zhou, J Sun, Y Huang, H Zheng, H Cao, X Zhou, S Guo … & X Zhang
The methylome reported and analyzed here was generated from the same sample of peripheral blood mononuclear cells (PBMCs) from a consented donor (Homo sapiens) whose genome was deciphered in the YH project. YH is an anonymous male Han Chinese individual who has no known genetic diseases, and whose genome also serves as an Asian reference genome. Nuclear DNA was extracted and subjected to unbiased, whole-genome bisulfite sequencing (BS-seq) using the Illumina Genome Analyzer. In total,...

1 Related Work

Genome sequence of YH: the first diploid genome sequence of a Han Chinese individual

J Wang, W Wang, R Li, Y Li, G Tian, L Goodman, W Fan, J Zhang, J Li, J Zhang, Y Guo, B Feng, H Li, Y Lu, X Fang, H Liang, Z Du, D Li, Y Zhao, Y Hu, Z Yang, H Zheng, I Hellmann, M Inouye, J Pool … & J Wang
Genomic data from the YH (Homo sapiens) genome – first diploid genome sequence of a Han Chinese, a representative of the Asian population. The genomic DNA used in this study came from an anonymous male Han Chinese individual who has no known genetic diseases. The YH genome was assembled based on 3.3 billion reads using the Illumina Genome Analyzer. We achieved 117.7G nucleotides data and the genome was sequenced to 36-fold average coverage. By aligning...

Resource Types

  • Dataset
    1

Publication Year

  • 2011
    1

Data Centers

  • Beijing Genomics Institute
    1