The role of Oxalobacter formigenes in calcium oxalate stone disease

Roswitha Siener
Calcium oxalate is the major component of about 75% of all urinary stones. Hyperoxaluria is a primary risk factor for calcium oxalate stone formation. The bioavailability of ingested oxalate and the extent of intestinal absorption of dietary oxalate are considered to be important factors in hyperoxaluria. Oxalobacter formigenes is a Gram-negative anaerobic bacterium that colonizes the intestinal tract. It is unique in that it requires oxalate both as an energy and carbon source. The only...
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