Principles of Micellar Electrokinetic Capillary Chromatography Applied in Pharmaceutical Analysis

Gabriel Hancu, Brigitta Simon, Aura Rusu, Eleonora Mircia & Árpád Gyéresi
Since its introduction capillary electrophoresis has shown great potential in areas where electrophoretic techniques have rarely been used before, including here the analysis of pharmaceutical substances. The large majority of pharmaceutical substances are neutral from electrophoretic point of view, consequently separations by the classic capillary zone electrophoresis; where separation is based on the differences between the own electrophoretic mobilities of the analytes; are hard to achieve. Micellar electrokinetic capillary chromatography, a hybrid method that combines...