Investigation into Alternative Sugars as Potential Carriers for Dry Powder Formulation of Budesonide

Mohammed-Nurul Momin, Atoosa Hedayati & Ali Nokhodchi
Introduction: Dry powder inhaler (DPI) formulations are so far being used for pulmonary drug delivery, mainly for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Currently most of DPI formulations rely on lactose as a carrier in the drug powder blend. However, due to reducing sugar function of lactose which makes it incompatible with some drugs such as budesonide, it is realistic to investigate for alternative sugars that would overcome the concerned drawback...