Apoptosis Resistance in Endometriosis

Ali Salmassi, Bengi Acar-Perk, Andreas G. Schmutzler, Kerstin Koch, Frank Püngel, Walter Jonat & Liselotte Mettler
Introduction: In a cytological analysis of endometriotic lesions neither granulocytes nor cytotoxic T-cells appear in an appreciable number. Based on this observation we aimed to know, whether programmed cell death plays an essential role in the destruction of dystopic endometrium. Disturbances of the physiological mechanisms of apoptosis, a persistence of endometrial tissue could explain the disease. Another aspect of this consideration is the proliferation competence of the dystopic mucous membrane. Methods: Endometriotic lesions of 15...