An Update to Space Biomedical Research: Tissue Engineering in Microgravity Bioreactors

Abolfazl Barzegari & Amir Ata Saei
The severe need for replacement tissues in defective or injured organ transplantation has necessitated the development of tissue engineering approaches and bioreactors that can bring these approaches to reality. The inherent limitations of conventional bioreactors in generating realistic tissue constructs led to the devise of the microgravity tissue engineer-ing that uses Rotating Wall Vessel (RWV) bioreactors developed by NASA. Research is now focused on assembly of 3 dimensional (3D) tissue fragments from various cell types...