Promoters of Cancer Genes for Recombinant Protein Expression in Human Cancer Cell Lines

Mohammad Pourhassan-Moghaddam, Behrouz Farhadi, Kazem Nejati-Koshki & Tamouchin Moharrami
Introduction: Production of complex human recombinant proteins is an important issue in medical biotechnology. These proteins are mostly expressed in non-human mammalian host cells. This has some problems including non-human post-translational modifications, application of high-cost agents for inducing protein expression and low yields. Therefore, it is necessary to use new expression systems to overcome the indicated challenges. Me-thods: In this paper, we hypothesize the application of promoter regions of cancer genes, which have a high...