Reduced odds of diabetes associated with high plasma salivary α-amylase activity in Qatari women: a cross-sectional study

Neyla S. Al-Akl, Richard Ian Thompson & Abdelilah Arredouani
The association of salivary α-amylase activity (SAA) activity or low copy number of its coding gene AMY1 with diabetes remains controversial. We aimed to reinvestigate the association of these factors with diabetes in Qatar, where diabetes prevalence is about 16%. We obtained cross-sectional data of 929 Qataris (age > 18 years) from the Qatar Biobank. We estimated AMY1 copy number variants (CNV) from whole-genome data, and quantified the SAA activity in plasma (pSAA). We used...
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