The Roles of the Planar Cell Polarity Molecules Prickle1a and Prickle1b in Zebrafish Cranial Neural Crest

Kamil Ahsan
In this dissertation, I will discuss my investigation into the roles of two molecules, zebrafish Prickle1b and Prickle1a, part of a suite of proteins called Planar Cell Polarity (PCP) proteins, in the specific context of a multipotent stem cell population, the neural crest. Neural crest cells have been likened to metastatic cancer cells in how they invade regions of the developing embryo by traversing large distances and subsequently differentiating into many different cell types. PCP...
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