The Influence of Germline Genetic Variation on Early Onset Breast Cancer Incidence and Mortality

Molly Scannell Bryan
In the United States, breast cancer is the most frequently diagnosed non-skin cancer in women, and one in five women who are diagnosed develop breast cancer before age 50. Germline genetic variation is a known risk factor for breast cancer risk, and a suspected risk factor for breast cancer mortality, but previous investigations have not comprehensively identified all of the genetic variation that is expected to be associated with breast cancer. One possible explanation for...
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