Defining Myosin-10 Navigation Rules

Kevin Christopher Vavra
Myosin-10 an unconventional myosin motor that localizes to tips of filopodia, long finger- like projections from cells, to help relocate its cargo proteins to the tips and bodies of filopodia. While it is known that myosin-10 moves along filopodial actin, how myosin-10 specifically selects for filopodial actin tracks is currently unknown. Three research groups attempted to determine myosin-10’s track selection ability using single molecule techniques to measure myosin-10 actin bundle selection behavior. Due to the...
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