Data for clot degradation under the action of histotripsy bubble activity and a lytic drug

Samuel Hendley
Venous thromboembolism is a major source of morbidity worldwide, and the degree of intervention depends on the likelihood of sequalae. Iliofemoral thrombi can migrate to the pulmonary circulation, which has a high associated risk of mortality. The frontline treatment for deep vein thrombosis is recanalization with a catheter-directed fibrinolytic administered over the course of several hours. Prolonged exposure to fibrinolytic carries an increased risk of undue bleeding. Further, mature venous thrombi contain components that are...
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