Chemical Approaches to Decipher Transcription and RNA Metabolism

Tong Wu
Gene expression involves complex processes and determines cell fate and physiological functions. Dysfunction of gene expression regulation is associated with human diseases. Coupled with the next-generation sequencing, small-molecule probes and nucleic acid analogs have been widely involved in interrogating gene expression and its regulatory mechanisms in a high-throughput manner. Although powerful, existing techniques have different limitations, and the current chemical toolbox still needs to be expanded. My doctoral work focus on the development and applications...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.