Minimal Reconstitution of Actin Networks to Investigate Mechanisms of Actin Binding Proteins

Caitlin Ann Anderson
The actin cytoskeleton is a large, complex, dynamic network that is responsible for a myriad of cellular processes, including, polarity, endocytosis, motility, cytokinesis, and force response. Distinct filamentous actin (F-actin) networks assemble from one crowded cytoplasm. The ability to build several F-actin networks simultaneously with distinct architectures, dynamics, location, and timing is a topic that has drawn a lot of interest. Each of these F-actin networks associate with a set of actin binding proteins (ABPs)....
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