The Role of m6A mRNA Methylation in Oligodendrocyte Development, CNS Myelination, and Remyelination

Huan Xu
Oligodendrocytes are the myelin-forming cells in the central nervous system (CNS). Myelin is a multilayered membrane sheath structure that surrounds neuronal cell axons. Oligodendrocyte lineage cells and myelin are important for various CNS functions, such as electrical signal propagation and axonal metabolic support. Recent studies revealed oligodendrocyte lineage cells and myelin also play important roles in motor skill learning, memory and the aging process. Inherited and acquired myelination deficits such as leukodystrophies and multiple sclerosis...
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