Heteroatom Guided Total Synthesis: Application to Polyhalogenated and Polyoxygenated Natural Products

Cooper Ashley Taylor
Natural products and their derivatives account for 62% of all FDA-approved small molecules from 1981 to 2014. However, the use of natural products for pharmaceutical purposes is often limited by both the low natural abundance of such targets and general synthetic inefficiency in making complex molecules on scale. Herein, we hope to explore how we may surmount the latter limitation, as we discuss our efforts in the production of compounds with not only a high...
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