Central immunological position of the human histo (blood) group O(H).

Peter Arend

Prokaryotic "blood group A/B-like" antigenic structures apparently induce basically cross-reactive anti-A/B immunoglobulins, which due to clonal selection neither arise in blood group A nor in B individuals, and occur exclusively in blood group O. While bacterial endotoxins non-specifically stimulate the formation of all immunoglobulins, most likely involving the anti-A/B isoagglutinins, a definite, adaptive immunological induction of these agglutinins appears to be restricted to blood group O(H) individuals. In the non-O blood groups, anti-A/B reactivity is...

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Central immunological position of the human histo (blood) group O(H).

Peter Arend

Prokaryotic "blood group A/B-like" antigenic structures apparently induce basically cross-reactive anti-A/B immunoglobulins, which due to clonal selection neither arise in blood group A nor in B individuals but occur exclusively in blood group O. While bacterial endotoxins non-specifically stimulate the formation of all immunoglobulins, most likely involving the anti-A/B isoagglutinins, a definite, adaptive immunological induction of these agglutinins appears to be restricted to blood group O(H) individuals. In the non-O blood groups, anti-A/B reactivity is...

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