Cell kinetics in superficial squamous cell carcinoma of the skin: Role of mismatch repair proteins and telomerase

, , & Salvador J. Diaz-Cano
Background: The cell kinetics of superficial squamous cell carcinoma (SCC) has revealed controversial results due to the heterogeneity of lesions considered, making it more difficult to assess key elements in squamous cell tumor progression. This study analyzes kinetics, cell survival and mismatch repair in a series of high-grade intraepithelial and microinvasive SCC. Design: We selected bowenoid actinic keratosis (HG-AK, 22 cases), SCC in-situ (37 cases) and microinvasive SCC (<3mm depth, 36 cases) that had appropriate...
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