Evidence that the second human pegivirus (HPgV-2) is primarily a lymphotropic virus and can replicate independent of HCV replication

Zhengwei Wan, Junwei Liu, Fengyu Hu, Jingwei Shui, Linghua Li, Haiying Wang, Xiaoping Tang, Chengguang Hu, Yuanhao Liang, Yuanping Zhou, Weiping Cai & Shixing Tang
The second human pegivirus HPgV-2 is a novel blood-borne virus that is strongly associated with the hepatitis C virus (HCV) infection. However, the molecular evidence for their association as well as the natural history and tissue tropism of HPgV-2 remain to be elucidated. In this longitudinal study, a total of 753 patients including 512 HIV-1 and HCV co-infected patients were enrolled to characterize the natural history of HPgV-2 infection. Peripheral blood mononuclear cells (PBMCs) and...
1 citation reported since publication in 2021.
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