Surgical applications of intracorporal tissue adhesive agents: current evidence and future development

Nicholas Gillman, David Lloyd, Randy Bindra, Rui Ruan & Minghao Zheng
Introduction: Traditional mechanical closure techniques pose many challenges including the risk of infection, tissue reaction, and injury to both patients and clinicians. There is an urgent need to develop tissue adhesive agents to reform closure technique. This review examined a variety of tissue adhesive agents available in the market in an attempt to gain a better understanding of intracorporal tissue adhesive agents as medical devices. Areas covered: Fundamental principles and clinical determinants of the tissue...
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