Neurodegenerative Diversity in human cortical contusion: Histological analysis of tissue derived from decompressive craniectomy

David Riascos, Efraín Buriticá, Mauricio Palacios, , , Francisco Guzmán, Norberto Garcia-Cairasco, , Martha Escobar & Hernán Pimienta
The principal aim in the management of patients with cerebral contusion (CC) following severe traumatic brain injury (TBI) is the prevention, amelioration, and treatment of secondary neuronal dysfunction and pathology. Distinguishing between irreversibly damaged and surviving tissue could have considerable therapeutic and prognostic implications for patients. To characterize structurally the neuronal compartment of the contused region in samples derived from patients who suffered severe TBI and were subjected todecompressive craniectomy, we used NeuN, a neuronal...
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