Non-walled spherical Acinetobacter baumannii is an important type of persister upon β-lactam antibiotic treatment

Jin Zou, Si-Hoi Kou, Ruiqiang Xie, Michael S. VanNieuwenhze, Jiuxin Qu, Bo Peng & Jun Zheng
Bacterial persistence is one of the major causes of antibiotic treatment failure and the step stone for antibiotic resistance. However, the mechanism by which persisters arise has not been well understood. Maintaining a dormant state to prevent antibiotics from taking effect is believed to be the fundamental mechanistic basis, and persisters normally maintain an intact cellular structure. Here we examined the morphologies of persisters in Acinetobacter baumannii survived from the treatment by three major classes...
1 citation reported since publication in 2021.
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