High neutralizing antibody titer in intensive care unit patients with COVID-19

Li Liu, Kelvin Kai-Wang To, Kwok-Hung Chan, Yik-Chun Wong, Runhong Zhou, Ka-Yi Kwan, Carol Ho-Yan Fong, Lin-Lei Chen, Charlotte Yee-Ki Choi, Lu Lu, Owen Tak-Yin Tsang, Wai-Shing Leung, Wing-Kin To, Ivan Fan-Ngai Hung, Kwok-Yung Yuen & Zhiwei Chen
Coronavirus disease 2019 (COVID-19) has a wide spectrum of disease severity from mild upper respiratory symptoms to respiratory failure. The role of neutralizing antibody (NAb) response in disease progression remains elusive. This study determined the seroprevalence of 733 non-COVID-19 individuals from April 2018 to February 2020 in the Hong Kong Special Administrative Region and compared the neutralizing antibody (NAb) responses of eight COVID-19 patients admitted to the intensive care unit (ICU) with those of 42...
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